Ontology highlight
ABSTRACT:
SUBMITTER: Bi H
PROVIDER: S-EPMC5215899 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Bi Hongkai H Zhu Lei L Jia Jia J Zeng Liping L Cronan John E JE
Cell chemical biology 20161117 12
Helicobacter pylori is a Gram-negative bacterium that inhabits the upper gastrointestinal tract in humans, and the presence of this pathogen in the gut microbiome increases the risk of peptic ulcers and stomach cancer. H. pylori depends on unsaturated fatty acid (UFA) biosynthesis for maintaining membrane structure and function. Although some of the H. pylori enzymes involved in UFA biosynthesis are functionally homologous with the enzymes found in Escherichia coli, we show here that an enzyme H ...[more]