TOWARDS THE DEVELOPMENT OF NOVEL THERAPEUTICS FOR PERIPHERAL ARTERY DISEASE.
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ABSTRACT:
SUBMITTER: Annex BH
PROVIDER: S-EPMC5216482 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
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TOWARDS THE DEVELOPMENT OF NOVEL THERAPEUTICS FOR PERIPHERAL ARTERY DISEASE.
Annex Brian H BH Beller George A GA
Transactions of the American Clinical and Climatological Association 20160101
Atherosclerosis is the leading cause of morbidity and mortality in the Western world. Peripheral artery disease (PAD) has been less studied then coronary artery disease but is nearly as common. PAD impairs blood flow to the leg(s) and causes functional impairment, leg pain, and amputation. The last drug approved for PAD was in 1999. Blood flow to leg proceeds through one major artery and in PAD total occlusions in the course of that vessel are common. Thus, the extent of new blood vessel growth ...[more]
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