Ontology highlight
ABSTRACT:
SUBMITTER: Balandran JC
PROVIDER: S-EPMC5216624 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Balandrán Juan Carlos JC Purizaca Jessica J Enciso Jennifer J Dozal David D Sandoval Antonio A Jiménez-Hernández Elva E Alemán-Lazarini Leticia L Perez-Koldenkova Vadim V Quintela-Núñez Del Prado Henry H Rios de Los Ríos Jussara J Mayani Héctor H Ortiz-Navarrete Vianney V Guzman Monica L ML Pelayo Rosana R
Frontiers in immunology 20170105
Pediatric oncology, notably childhood acute lymphoblastic leukemia (ALL), is currently one of the health-leading concerns worldwide and a biomedical priority. Decreasing overall leukemia mortality in children requires a comprehensive understanding of its pathobiology. It is becoming clear that malignant cell-to-niche intercommunication and microenvironmental signals that control early cell fate decisions are critical for tumor progression. We show here that the mesenchymal stromal cell component ...[more]