Ontology highlight
ABSTRACT:
SUBMITTER: Shi Y
PROVIDER: S-EPMC5216997 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Shi Ying Y Huang Xiao-Xiao XX Chen Guo-Bin GB Wang Ying Y Zhi Qiang Q Liu Yuan-Sheng YS Wu Xiao-Ling XL Wang Li-Fen LF Yang Bing B Xiao Chuan-Xing CX Xing Hui-Qin HQ Ren Jian-Lin JL Xia Yin Y Guleng Bayasi B
Oncotarget 20160701 30
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and a major cause of cancer mortality. Chemotherapy resistance remains a major challenge for treating advanced CRC. Therefore, the identification of targets that induce drug resistance is a priority for the development of novel agents to overcome resistance. Dragon (also known as RGMb) is a member of the repulsive guidance molecule (RGM) family. We previously showed that Dragon expression increases with CRC progression in huma ...[more]