Dataset Information

Association of Hip Bone Mineral Density and Body Composition in a Rural Indian Population: The Andhra Pradesh Children and Parents Study (APCAPS).

ABSTRACT:

Background

Fat mass is variably associated with bone mass, possibly due to differential mechanical and biological effects of fat mass. We examined the association of fat mass with bone mass in a lean population.

Objective

To investigate association between hip bone mineral density and fat and lean mass in a cross-sectional study from southern India.

Design

The Andhra Pradesh Children and Parents Study is a prospective cohort study in Hyderabad, India. In 2009-2012, the study collected data on anthropometric measures, bone mineral density (BMD), fat mass, and lean mass measured by dual-energy x-ray absorptiometry, and socioeconomic data of the adult participants (n = 1760; mean age = 34.9 years old for women; 2130 and 32.3 for men).

Results

The median BMI (kg/m2) was 20.1 kg/m2. Women had relatively higher fat mass as compared to men. In models adjusted for lean mass, there was an association between hip bone mineral density and fat mass in women (? (95% confidence interval): premenopausal 0.025 (0.006 to 0.045); postmenopausal 0.045 (0.014 to 0.076)) but not in men (0.001 (-0.012 to 0.0014)). The association between hip BMD and fat mass was stronger in postmenopausal than premenopausal women. Hip BMD was consistently associated with lean mass, in both men and women.

Conclusions

In this relatively lean population, lean mass was more consistently associated with hip BMD than fat mass. Weight gain through lean mass improvement may be a more reliable public health strategy for strengthening bone health in transitional settings.

SUBMITTER: Matsuzaki M

PROVIDER: S-EPMC5217858 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Publications

Association of Hip Bone Mineral Density and Body Composition in a Rural Indian Population: The Andhra Pradesh Children and Parents Study (APCAPS).

Matsuzaki Mika M Kulkarni Bharati B Kuper Hannah H Wells Jonathan C JC Ploubidis George B GB Prabhakaran Poornima P Gupta Vipin V Walia Gagandeep Kaur GK Aggarwal Aastha A Prabhakaran Dorairaj D Davey Smith George G Radhakrishna Kankipati Vijaya KV Ben-Shlomo Yoav Y Kinra Sanjay S

PloS one 20170106 1

<h4>Background</h4>Fat mass is variably associated with bone mass, possibly due to differential mechanical and biological effects of fat mass. We examined the association of fat mass with bone mass in a lean population.<h4>Objective</h4>To investigate association between hip bone mineral density and fat and lean mass in a cross-sectional study from southern India.<h4>Design</h4>The Andhra Pradesh Children and Parents Study is a prospective cohort study in Hyderabad, India. In 2009-2012, the stud ...[more]

PMID: 28060826

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Dataset Information

Association of Hip Bone Mineral Density and Body Composition in a Rural Indian Population: The Andhra Pradesh Children and Parents Study (APCAPS).

Background

Objective

Design

Results

Conclusions

Publications

Association of Hip Bone Mineral Density and Body Composition in a Rural Indian Population: The Andhra Pradesh Children and Parents Study (APCAPS).

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