Ontology highlight
ABSTRACT:
SUBMITTER: Podyma-Inoue KA
PROVIDER: S-EPMC5219918 | biostudies-literature | 2016 11-12
REPOSITORIES: biostudies-literature
Podyma-Inoue Katarzyna A KA Moriwaki Takuya T Rajapakshe Anupama R AR Terasawa Kazue K Hara-Yokoyama Miki M
Cancer genomics & proteomics 20160101 6
<h4>Background</h4>Heparan sulfate proteoglycans (HSPGs)-dependent endocytic events have been involved in glioma progression. Thus, comprehensive understanding of the intracellular trafficking complexes formed in presence of HSPGs would be important for development of glioma treatments.<h4>Materials and methods</h4>Subcellular fractionation was used to separate vesicles containing HSPGs from the rat C6 glioma cell line. Isolated HSPG-positive vesicles were further characterized with liquid chrom ...[more]