Darwinian adaptation of proteorhodopsin to different light intensities in the marine environment.
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ABSTRACT:
SUBMITTER: Bielawski JP
PROVIDER: S-EPMC522022 | biostudies-literature | 2004 Oct
REPOSITORIES: biostudies-literature
Publications
Darwinian adaptation of proteorhodopsin to different light intensities in the marine environment.
Bielawski Joseph P JP Dunn Katherine A KA Sabehi Gazalah G Béjà Oded O
Proceedings of the National Academy of Sciences of the United States of America 20041004 41
Proteorhodopsin, a retinal-binding protein, represents a potentially significant source of light-driven energy production in the world's oceans. The distribution of photochemically divergent proteorhodopsins is stratified according to depth. Here, we present evidence that such photochemical diversity was tuned by Darwinian selection. By using a Bayesian method, we identified sites targeted by Darwinian selection and mapped them to three-dimensional models of proteorhodopsins. We suggest that spe ...[more]
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