Ontology highlight
ABSTRACT:
SUBMITTER: Lin H
PROVIDER: S-EPMC5220313 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Scientific reports 20170109
Atrial fibrillation (AF) is the most common cardiac arrhythmia, but little is known about the molecular mechanisms associated with AF arrhythmogenesis. DNA methylation is an important epigenetic mechanism that regulates gene expression and downstream biological processes. We hypothesize that DNA methylation might play an important role in the susceptibility to develop AF. A total of 2,639 participants from the Offspring Cohort of Framingham Heart Study were enrolled in the current study. These p ...[more]