Repeated mild traumatic brain injury causes focal response in lateral septum and hippocampus.
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ABSTRACT:
SUBMITTER: Acabchuk R
PROVIDER: S-EPMC5222510 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
Repeated mild traumatic brain injury causes focal response in lateral septum and hippocampus.
Acabchuk Rebecca R Briggs Denise I DI Angoa-Pérez Mariana M Powers Meghan M Wolferz Richard R Soloway Melanie M Stern Mai M Talbot Lillian R LR Kuhn Donald M DM Conover Joanne C JC
Concussion (London, England) 20160525 3
<h4>Aim</h4>To advance our understanding of regional and temporal cellular responses to repeated mild traumatic brain injury (rmTBI), we used a mouse model of rmTBI that incorporated acceleration, deceleration and rotational forces.<h4>Materials & methods</h4>A modified weight-drop method was used to compare two inter-injury intervals, rmTBI-short (five hits delivered over 3 days) and rmTBI-long (five hits delivered over 15 days). Regional investigations of forebrain and midbrain histological al ...[more]
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