Ontology highlight
ABSTRACT:
SUBMITTER: Hollaus R
PROVIDER: S-EPMC5223274 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Organic letters 20161223 1
Stereoselective synthesis of variably protected α- and β-l-Ara4N glycosyl H-phosphonates as key intermediates in the syntheses of β-l-Ara4N-modified LPS structures and α-l-Ara4N-containing biosynthetic precursors is reported. A facile one-pot approach toward β-l-Ara4N glycosyl H-phosphonates includes anomeric deallylation of protected 4-azido β-l-Ara4N via terminal olefin isomerization followed by ozonolysis and methanolysis of formyl groups to furnish exclusively β-configured lactols that are p ...[more]