Epidemiological survey of the feasibility of broadband ultrasound attenuation measured using calcaneal quantitative ultrasound to predict the incidence of falls in the middle aged and elderly.
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ABSTRACT: OBJECTIVES:We investigated whether calcaneal quantitative ultrasound (QUS-C) is a feasible tool for predicting the incidence of falls. DESIGN:Prospective epidemiological cohort study. SETTING:Community-dwelling people sampled in central western Taiwan. PARTICIPANTS:A cohort of community-dwelling people who were ?40?years old (men: 524; women: 676) in 2009-2010. Follow-up questionnaires were completed by 186 men and 257 women in 2012. METHODS:Structured questionnaires and broadband ultrasound attenuation (BUA) data were obtained in 2009-2010 using QUS-C, and follow-up surveys were done in a telephone interview in 2012. Using a binary logistic regression model, the risk factors associated with a new fall during follow-up were analysed with all significant variables from the bivariate comparisons and theoretically important variables. PRIMARY OUTCOME MEASURES:The incidence of falls was determined when the first new fall occurred during the follow-up period. The mean follow-up time was 2.83?years. RESULTS:The total incidence of falls was 28.0 per 1000 person-years for the ?40?year old group (all participants), 23.3 per 1000 person-years for the 40-70?year old group, and 45.6 per 1000 person-years for the ?70?year old group. Using multiple logistic regression models, the independent factors were current smoking, living alone, psychiatric drug usage and lower BUA (OR 0.93; 95% CI 0.88 to 0.99, p<0.05) in the ?70?year old group. CONCLUSIONS:The incidence of falls was highest in the ?70?year old group. Using QUS-C-derived BUA is feasible for predicting the incidence of falls in community-dwelling elderly people aged ?70?years.
SUBMITTER: Ou LC
PROVIDER: S-EPMC5223632 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
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