Ontology highlight
ABSTRACT:
SUBMITTER: Buzdin AA
PROVIDER: S-EPMC5224468 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Buzdin Anton A AA Artcibasova Alina V AV Fedorova Natalya F NF Suntsova Maria V MV Garazha Andrew V AV Sorokin Maxim I MI Allina Daria D Shalatonin Mikhail M Borisov Nikolay M NM Zhavoronkov Alex A AA Kovalchuk Igor I Kovalchuk Olga O Kushch Alla A AA
Cell cycle (Georgetown, Tex.) 20161201 24
Responses to human cytomegalovirus (HCMV) infection are largely individual and cell type specific. We investigated molecular profiles in 2 primary cell cultures of human fibroblasts, which are highly or marginally sensitive to HCMV infection, respectively. We screened expression of genes and microRNAs (miRs) at the early (3 hours) stage of infection. To assess molecular pathway activation profiles, we applied bioinformatic algorithms OncoFinder and MiRImpact. In both cell types, pathway regulati ...[more]