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Characterization of genes and pathways that respond to heat stress in Holstein calves through transcriptome analysis.


ABSTRACT: This study aimed to investigate the genes and pathways that respond to heat stress in Holstein bull calves exposed to severe ranges of temperature and humidity. A total of ten animals from 4 to 6 months of age were subjected to heat stress at 37 °C and 90 % humidity for 12 h. Skin and rectal temperatures were measured before and after heat stress; while no correlation was found between them before heat stress, a moderate correlation was detected after heat stress, confirming rectal temperature to be a better barometer for monitoring heat stress. RNAseq analysis identified 8567 genes to be differentially regulated, out of which 465 genes were significantly upregulated (?2-fold, P?

SUBMITTER: Srikanth K 

PROVIDER: S-EPMC5225057 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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Characterization of genes and pathways that respond to heat stress in Holstein calves through transcriptome analysis.

Srikanth Krishnamoorthy K   Kwon Anam A   Lee Eunjin E   Chung Hoyoung H  

Cell stress & chaperones 20161116 1


This study aimed to investigate the genes and pathways that respond to heat stress in Holstein bull calves exposed to severe ranges of temperature and humidity. A total of ten animals from 4 to 6 months of age were subjected to heat stress at 37 °C and 90 % humidity for 12 h. Skin and rectal temperatures were measured before and after heat stress; while no correlation was found between them before heat stress, a moderate correlation was detected after heat stress, confirming rectal temperature t  ...[more]

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