Ontology highlight
ABSTRACT:
SUBMITTER: Bakhit YH
PROVIDER: S-EPMC5227114 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Bakhit Yousuf Hasan Yousuf YH Ibrahim Mohamed Osama Mirghani MO Amin Mutaz M Mirghani Yousra Abdelazim YA Hassan Mohamed Ahmed Salih MA
Advances in bioinformatics 20161229
<i>Introduction</i>. Parkinson's disease (PD) is a common neurodegenerative disorder. Mutations in <i>PINK1</i> are the second most common agents causing autosomal recessive, early onset PD. We aimed to identify the pathogenic SNPs in <i>PARK2</i> and <i>PINK1</i> using in silico prediction software and their effect on the structure, function, and regulation of the proteins. <i>Materials and Methods</i>. We carried out in silico prediction of structural effect of each SNP using different bioinfo ...[more]