Kidney dysfunction, systemic inflammation and mental well-being in elderly post-myocardial infarction patients.

ABSTRACT:

Background

The aim was to investigate whether mild kidney dysfunction and low-grade inflammation in post-myocardial infarction patients are independently associated with markers of mental well-being (i.e. depressive and apathy symptoms, and dispositional optimism).

Methods

In post-myocardial infarction patients, kidney function was assessed by estimated glomerular filtration rate (eGFR) calculated from the combined CKD-EPI formula based on serum levels of both creatinine and cystatine C. Systemic inflammation was assessed using high sensitivity C-reactive protein (hs-CRP) levels. The 15-item Geriatric Depression Scale (GDS-15), the 3-item apathy subscale and the 4-item optimism questionnaire (4Q) were used to measure mental well-being and were analyzed using linear multivari

SUBMITTER: Heeres RH 

PROVIDER: S-EPMC5228176 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature