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Dexmedetomidine prevent postoperative nausea and vomiting on patients during general anesthesia: A PRISMA-compliant meta analysis of randomized controlled trials.
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ABSTRACT: Background
Postoperative nausea and vomiting (PONV) is a frequent complication in postoperative period. The aim of this article was to evaluate the effect of dexmedetomidine on PONV.Method
RevMan 5.3 software was applied for performing statistic analysis. Twenty-four trials with 2046 patients were included.Results
The PONV of the dexmedetomidine group was significantly lower compared with the placebo group (0.56, 95% CI: 0.46, 0.69). Subgroup analysis further confirmed the effect of dexmedetomidine (irrespective of administration mode) (P?ConclusionsDexmedetomidine administrated in continuous infusion mode has the advantage to prevent PONV as well as reduce side effects such as bradycardia and hypotension.
SUBMITTER: Jin S
PROVIDER: S-EPMC5228682 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Publications
Dexmedetomidine prevent postoperative nausea and vomiting on patients during general anesthesia: A PRISMA-compliant meta analysis of randomized controlled trials.
Medicine 20170101 1
<h4>Background</h4>Postoperative nausea and vomiting (PONV) is a frequent complication in postoperative period. The aim of this article was to evaluate the effect of dexmedetomidine on PONV.<h4>Method</h4>RevMan 5.3 software was applied for performing statistic analysis. Twenty-four trials with 2046 patients were included.<h4>Results</h4>The PONV of the dexmedetomidine group was significantly lower compared with the placebo group (0.56, 95% CI: 0.46, 0.69). Subgroup analysis further confirmed th ...[more]