Ontology highlight
ABSTRACT:
SUBMITTER: Gaudet J
PROVIDER: S-EPMC523228 | biostudies-literature | 2004 Nov
REPOSITORIES: biostudies-literature
Gaudet Jeb J Muttumu Srikanth S Horner Michael M Mango Susan E SE
PLoS biology 20041019 11
We have investigated the cis-regulatory network that mediates temporal gene expression during organogenesis. Previous studies demonstrated that the organ selector gene pha-4/FoxA is critical to establish the onset of transcription of Caenorhabditis elegans foregut (pharynx) genes. Here, we discover additional cis-regulatory elements that function in combination with PHA-4. We use a computational approach to identify candidate cis-regulatory sites for genes activated either early or late during p ...[more]