The interleukin-6-hepcidin-hemoglobin circuit in systemic lupus erythematosus flares.
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ABSTRACT:
SUBMITTER: Indrakanti DL
PROVIDER: S-EPMC5237426 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
The interleukin-6-hepcidin-hemoglobin circuit in systemic lupus erythematosus flares.
Indrakanti D L DL Alvarado A A Zhang X X Birmingham D J DJ Hinton A A Rovin B H BH
Lupus 20160720 2
Objective Hepcidin regulates iron availability and may be responsible for the anemia of chronic disease because it is induced by interleukin-6. This study investigated the IL-6-hepcidin-hemoglobin axis in patients with lupus. Methods IL-6 and hepcidin were measured in serial serum samples collected before, during and after lupus flares by specific ELISAs. Results During renal and non-renal SLE flare cycles IL-6 did not predict hepcidin and hepcidin did not predict hemoglobin. When lupus nephriti ...[more]
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Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
2014-06-03 | E-GEOD-46923 | biostudies-arrayexpress
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