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Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study.


ABSTRACT: BACKGROUND:The novel group treatment program Training for Awareness, Resilience, and Action (TARA) was developed to target specific mechanisms based on neuroscience findings in adolescent depression and framed within the National Institute of Mental Health Research Domain Criteria. TARA contains training of autonomic and emotional self-regulation, interoceptive awareness, relational skills, and value-based committed action. METHODS:We performed a single-arm trial to test the feasibility and preliminary efficacy of TARA in reducing depression and anxiety levels and assessed whether the specific targeted domains of function reflected the hypothesized symptom change. Twenty-six adolescents (14-18?years old, 7 males and 19 females) participated in the 12-week group program. Assessment was performed before (T0), immediately after (T1), and 3?months after the end of TARA (T2). RESULTS:Significant improvement was seen in depression symptoms (Reynolds Adolescent Depression Scale Second Edition) between T0-T1 (t-value?=?-3.56, p?=?0.002, CI?=?-6.64, -1.77) and T0-T2 (t-value?=?-4.17, p?

SUBMITTER: Henje Blom E 

PROVIDER: S-EPMC5237634 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study.

Henje Blom Eva E   Tymofiyeva Olga O   Chesney Margaret A MA   Ho Tiffany C TC   Moran Patricia P   Connolly Colm G CG   Duncan Larissa G LG   Baldini Lisa L   Weng Helen Y HY   Acree Michael M   Goldman Veronica V   Hecht Frederick M FM   Yang Tony T TT  

Frontiers in psychiatry 20170116


<h4>Background</h4>The novel group treatment program Training for Awareness, Resilience, and Action (TARA) was developed to target specific mechanisms based on neuroscience findings in adolescent depression and framed within the National Institute of Mental Health Research Domain Criteria. TARA contains training of autonomic and emotional self-regulation, interoceptive awareness, relational skills, and value-based committed action.<h4>Methods</h4>We performed a single-arm trial to test the feasi  ...[more]

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