Ontology highlight
ABSTRACT:
SUBMITTER: Guthoff M
PROVIDER: S-EPMC5238426 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Guthoff Martina M Wagner Robert R Randrianarisoa Elko E Hatziagelaki Erifili E Peter Andreas A Häring Hans-Ulrich HU Fritsche Andreas A Heyne Nils N
Scientific reports 20170116
Early identification of patients at risk of developing diabetic nephropathy is essential. Elevated serum concentrations of soluble urokinase receptor (suPAR) associate with diabetes mellitus and predict onset and loss of renal function in chronic kidney disease. We hypothesize, that suPAR may be an early risk indicator for diabetic nephropathy, preceding microalbuminuria. The relationship of baseline suPAR and incident microalbuminuria was assessed in a prospective long-term cohort of subjects a ...[more]