Ontology highlight
ABSTRACT:
SUBMITTER: Wu PT
PROVIDER: S-EPMC5238506 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Scientific reports 20170116
Evidence indicates that hyaluronic acid (HA) mitigates tendinopathy, but the effect of molecular weight is unclear. We investigated the effects of different concentrations and different molecular weights of HA (350 kDa, 1500 kDa, and 3000 kDa) on matrix metalloproteinase (MMP)-1 and -3 expression in IL-1β-stimulated rat tenocytes, and on their dynamic expression in peritendinous effusion from patients with long head of biceps (LHB) tendinopathy after high-molecular-weight (HMW)-HA treatments. Re ...[more]