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Slow generation of hydrogen sulfide from sulfane sulfurs and NADH models.

ABSTRACT: Here we report the model studies of the reactions between NADH models (using HEH and BNAH) and sulfane sulfurs (using polysulfides). Such reactions could lead to the oxidation of NADH models and the production of hydrogen sulfide (H2S). Kinetics of the reaction between BNAH and elemental sulfur S8 were determined in ethanol and the second-order rate constant was found to be 0.074M-1min-1 (at 37°C) suggesting this is a slow process.

SUBMITTER: Peng B

PROVIDER: S-EPMC5241217 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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Slow generation of hydrogen sulfide from sulfane sulfurs and NADH models.

Peng Bo B Liu Chunrong C Li Zhen Z Day Jacob J JJ Lu Yun Y Lefer David J DJ Xian Ming M

Bioorganic & medicinal chemistry letters 20161209 3

Here we report the model studies of the reactions between NADH models (using HEH and BNAH) and sulfane sulfurs (using polysulfides). Such reactions could lead to the oxidation of NADH models and the production of hydrogen sulfide (H2S). Kinetics of the reaction between BNAH and elemental sulfur S8 were determined in ethanol and the second-order rate constant was found to be 0.074M-1min-1 (at 37°C) suggesting this is a slow process. ...[more]

PMID: 28003140

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