Conservation of adjacency as evidence of paralogous operons.
Ontology highlight
ABSTRACT:
SUBMITTER: Janga SC
PROVIDER: S-EPMC524292 | biostudies-literature | 2004
REPOSITORIES: biostudies-literature
Publications
Conservation of adjacency as evidence of paralogous operons.
Janga Sarath Chandra SC Moreno-Hagelsieb Gabriel G
Nucleic acids research 20041011 18
Most of the analyses on the conservation of gene order are limited to orthologous genes. However, the organization of genes into operons might also result in the conservation of gene order of paralogous genes. Thus, we sought computational evidence that conservation of gene order of paralogous genes represents another level of conservation of genes in operons. We found that pairs of genes within experimentally characterized operons of Escherichia coli K12 and Bacillus subtilis tend to have more ...[more]
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