Ontology highlight
ABSTRACT:
SUBMITTER: Schmitz J
PROVIDER: S-EPMC524414 | biostudies-literature | 2004 Oct
REPOSITORIES: biostudies-literature
Schmitz Jürgen J Churakov Gennady G Zischler Hans H Brosius Jürgen J
Genome research 20040913 10A
In addition to their central function in protein biosynthesis, tRNAs also play a pervasive role in genome evolution and architecture because of their extensive ability to serve as templates for retroposition. Close to half of the human genome consists of discernible transposable elements, a vast majority of which are derived from RNA via reverse transcription and genomic integration. Apart from the presence of direct repeats (DRs) that flank the integrated sequence of retroposons, genomic integr ...[more]