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Metabolomics and Metabolic Diseases: Where Do We Stand?


ABSTRACT: Metabolomics, or the comprehensive profiling of small molecule metabolites in cells, tissues, or whole organisms, has undergone a rapid technological evolution in the past two decades. These advances have led to the application of metabolomics to defining predictive biomarkers for incident cardiometabolic diseases and, increasingly, as a blueprint for understanding those diseases' pathophysiologic mechanisms. Progress in this area and challenges for the future are reviewed here.

SUBMITTER: Newgard CB 

PROVIDER: S-EPMC5245686 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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Metabolomics and Metabolic Diseases: Where Do We Stand?

Newgard Christopher B CB  

Cell metabolism 20161027 1


Metabolomics, or the comprehensive profiling of small molecule metabolites in cells, tissues, or whole organisms, has undergone a rapid technological evolution in the past two decades. These advances have led to the application of metabolomics to defining predictive biomarkers for incident cardiometabolic diseases and, increasingly, as a blueprint for understanding those diseases' pathophysiologic mechanisms. Progress in this area and challenges for the future are reviewed here. ...[more]

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