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Organizing conceptual knowledge in humans with a gridlike code.


ABSTRACT: It has been hypothesized that the brain organizes concepts into a mental map, allowing conceptual relationships to be navigated in a manner similar to that of space. Grid cells use a hexagonally symmetric code to organize spatial representations and are the likely source of a precise hexagonal symmetry in the functional magnetic resonance imaging signal. Humans navigating conceptual two-dimensional knowledge showed the same hexagonal signal in a set of brain regions markedly similar to those activated during spatial navigation. This gridlike signal is consistent across sessions acquired within an hour and more than a week apart. Our findings suggest that global relational codes may be used to organize nonspatial conceptual representations and that these codes may have a hexagonal gridlike pattern when conceptual knowledge is laid out in two continuous dimensions.

SUBMITTER: Constantinescu AO 

PROVIDER: S-EPMC5248972 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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Organizing conceptual knowledge in humans with a gridlike code.

Constantinescu Alexandra O AO   O'Reilly Jill X JX   Behrens Timothy E J TEJ  

Science (New York, N.Y.) 20160616 6292


It has been hypothesized that the brain organizes concepts into a mental map, allowing conceptual relationships to be navigated in a manner similar to that of space. Grid cells use a hexagonally symmetric code to organize spatial representations and are the likely source of a precise hexagonal symmetry in the functional magnetic resonance imaging signal. Humans navigating conceptual two-dimensional knowledge showed the same hexagonal signal in a set of brain regions markedly similar to those act  ...[more]

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