Ontology highlight
ABSTRACT:
SUBMITTER: Townsend R
PROVIDER: S-EPMC5250646 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Townsend Robert R Desai Amit A Rammelsberg Diane D Kowalski Donna D Simmons Neal N Kitt Therese M TM
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20151125 1
<h4>Background</h4>Regadenoson is a selective A<sub>2A</sub> adenosine receptor agonist indicated for radionuclide myocardial perfusion imaging in patients unable to undergo adequate exercise stress. However, the safety, tolerability, and plasma concentrations associated with repeated doses have not previously been assessed.<h4>Method and results</h4>Healthy males and females were randomized to receive intravenous regadenoson [100 μg (3 doses), 200 μg (3 doses), or 400 μg (2 doses)], or placebo ...[more]