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Mycobacterium avium subsp. paratuberculosis strains isolated from Crohn's disease patients and animal species exhibit similar polymorphic locus patterns.


ABSTRACT: Analysis of short sequence repeats of Mycobacterium avium subsp. paratuberculosis isolated from Crohn's disease patients identified two alleles, both of which clustered with strains derived from animals with Johne's disease. Identification of a limited number of genotypes among human strains implies the existence of human disease-associated genotypes and strain sharing with animals.

SUBMITTER: Ghadiali AH 

PROVIDER: S-EPMC525262 | biostudies-literature | 2004 Nov

REPOSITORIES: biostudies-literature

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Mycobacterium avium subsp. paratuberculosis strains isolated from Crohn's disease patients and animal species exhibit similar polymorphic locus patterns.

Ghadiali Alifiya H AH   Strother Megan M   Naser Saleh A SA   Manning Elizabeth J B EJ   Sreevatsan Srinand S  

Journal of clinical microbiology 20041101 11


Analysis of short sequence repeats of Mycobacterium avium subsp. paratuberculosis isolated from Crohn's disease patients identified two alleles, both of which clustered with strains derived from animals with Johne's disease. Identification of a limited number of genotypes among human strains implies the existence of human disease-associated genotypes and strain sharing with animals. ...[more]

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