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Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

ABSTRACT: A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 beta-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 beta-lactamase by an Enterobacter sp.

SUBMITTER: Hossain A

PROVIDER: S-EPMC525415 | biostudies-literature | 2004 Nov

REPOSITORIES: biostudies-literature

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Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter sp.

Hossain Ashfaque A Ferraro M J MJ Pino R M RM Dew R B RB Moland E S ES Lockhart T J TJ Thomson K S KS Goering R V RV Hanson N D ND

Antimicrobial agents and chemotherapy 20041101 11

A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 beta-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 beta-lactamase by an Enterobacter sp. ...[more]

PMID: 15504876

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