Ontology highlight
ABSTRACT:
SUBMITTER: Dai M
PROVIDER: S-EPMC5256103 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Dai Miao M Zhu Xiao-Lu XL Liu Fei F Xu Qin-Yang QY Ge Qiu-Lin QL Jiang Shu-Heng SH Yang Xiao-Mei XM Li Jun J Wang Ya-Hui YH Wu Qing-Kai QK Ai Zhi-Hong ZH Teng Yin-Cheng YC Zhang Zhi-Gang ZG
Scientific reports 20170123
3β-Hydroxysteroid-Δ24 reductase (DHCR24), the final enzyme of the cholesterol biosynthetic pathway, has been associated with urogenital neoplasms. However, the function of DHCR24 in endometrial cancer (EC) remains largely elusive. Here, we analyzed the expression profile of DHCR24 and the progesterone receptor (PGR) in our tissue microarray of EC (n = 258), the existing EC database in GEO (Gene Expression Omnibus), and TCGA (The Cancer Genome Atlas). We found that DHCR24 was significantly elevat ...[more]