Ontology highlight
ABSTRACT:
SUBMITTER: Finkel RS
PROVIDER: S-EPMC5258738 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Journal of child neurology 20161022 2
The natural history of spinal muscular atrophy type I (SMA-I) has changed as improved medical support has become available. With investigational drugs for spinal muscular atrophy now in clinical trials, efficient trial design focuses on enrolling recently diagnosed infants, providing best available supportive care, and minimizing subject variation. The quandary has arisen whether it is ethically appropriate to specify a predefined level of nutritional and/or ventilation support for spinal muscul ...[more]