Ontology highlight
ABSTRACT:
SUBMITTER: Huang SH
PROVIDER: S-EPMC5259716 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Huang Shan-Han SH Tung Chun-Wei CW
Scientific reports 20170124
The assessment of non-genotoxic hepatocarcinogens (NGHCs) is currently relying on two-year rodent bioassays. Toxicogenomics biomarkers provide a potential alternative method for the prioritization of NGHCs that could be useful for risk assessment. However, previous studies using inconsistently classified chemicals as the training set and a single microarray dataset concluded no consensus biomarkers. In this study, 4 consensus biomarkers of A2m, Ca3, Cxcl1, and Cyp8b1 were identified from four la ...[more]