Ontology highlight
ABSTRACT:
SUBMITTER: Theron L
PROVIDER: S-EPMC5260965 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Théron Laëtitia L Centeno Delphine D Coudy-Gandilhon Cécile C Pujos-Guillot Estelle E Astruc Thierry T Rémond Didier D Barthelemy Jean-Claude JC Roche Frédéric F Feasson Léonard L Hébraud Michel M Béchet Daniel D Chambon Christophe C
Proteomes 20161026 4
Mass spectrometry imaging (MSI) is a powerful tool to visualize the spatial distribution of molecules on a tissue section. The main limitation of MALDI-MSI of proteins is the lack of direct identification. Therefore, this study focuses on a MSI~LC-MS/MS-LF workflow to link the results from MALDI-MSI with potential peak identification and label-free quantitation, using only one tissue section. At first, we studied the impact of matrix deposition and laser ablation on protein extraction from the t ...[more]