Dataset Information

The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis.

ABSTRACT:

Objective

To evaluate the effectiveness of a service for early psychosis.

Design

Randomised controlled clinical trial.

Setting

Community mental health teams in one London borough.

Participants

144 people aged 16-40 years presenting to mental health services for the first or second time with non-organic, non-affective psychosis.

Interventions

Assertive outreach with evidence based biopsychosocial interventions (specialised care group) and standard care (control group) delivered by community mental health teams.

Primary outcome measures

Rates of relapse and readmission to hospital.

Results

Compared with patients in the standard care group, those in the specialised care group were less likely to relapse (odds ratio 0.46, 95% confidence interval 0.22 to 0.97), were readmitted fewer times (beta 0.39, 0.10 to 0.68), and were less likely to drop out of the study (odds ratio 0.35, 0.15 to 0.81). When rates were adjusted for sex, previous psychotic episode, and ethnicity, the difference in relapse was no longer significant (odds ratio 0.55, 0.24 to 1.26); only total number of readmissions (beta 0.36, 0.04 to 0.66) and dropout rates (beta 0.28, 0.12 to 0.73) remained significant.

Conclusions

Limited evidence shows that a team delivering specialised care for patients with early psychosis is superior to standard care for maintaining contact with professionals and for reducing readmissions to hospital. No firm conclusions can, however, be drawn owing to the modest sample size.

SUBMITTER: Craig TK

PROVIDER: S-EPMC526115 | biostudies-literature | 2004 Nov

REPOSITORIES: biostudies-literature

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Publications

The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis.

Craig Tom K J TK Garety Philippa P Power Paddy P Rahaman Nikola N Colbert Susannah S Fornells-Ambrojo Miriam M Dunn Graham G

BMJ (Clinical research ed.) 20041014 7474

<h4>Objective</h4>To evaluate the effectiveness of a service for early psychosis.<h4>Design</h4>Randomised controlled clinical trial.<h4>Setting</h4>Community mental health teams in one London borough.<h4>Participants</h4>144 people aged 16-40 years presenting to mental health services for the first or second time with non-organic, non-affective psychosis.<h4>Interventions</h4>Assertive outreach with evidence based biopsychosocial interventions (specialised care group) and standard care (control ...[more]

PMID: 15485934

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Dataset Information

The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis.

Objective

Design

Setting

Participants

Interventions

Primary outcome measures

Results

Conclusions

Publications

The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis.

Similar Datasets

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