Genomic structural variations for cardiovascular and metabolic comorbidity.
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ABSTRACT:
SUBMITTER: Nazarenko MS
PROVIDER: S-EPMC5264603 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Publications
Genomic structural variations for cardiovascular and metabolic comorbidity.
Nazarenko Maria S MS Sleptcov Aleksei A AA Lebedev Igor N IN Skryabin Nikolay A NA Markov Anton V AV Golubenko Maria V MV Koroleva Iuliia A IA Kazancev Anton N AN Barbarash Olga L OL Puzyrev Valery P VP
Scientific reports 20170125
The objective of this study was to identify genes targeted by both copy number and copy-neutral changes in the right coronary arteries in the area of advanced atherosclerotic plaques and intact internal mammary arteries derived from the same individuals with comorbid coronary artery disease and metabolic syndrome. The artery samples from 10 patients were screened for genomic imbalances using array comparative genomic hybridization. Ninety high-confidence, identical copy number variations (CNVs) ...[more]
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