Production of Heteromeric Transmembrane Receptors with Defined Subunit Stoichiometry.
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ABSTRACT:
SUBMITTER: Malinauskas T
PROVIDER: S-EPMC5266497 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Publications
Production of Heteromeric Transmembrane Receptors with Defined Subunit Stoichiometry.
Malinauskas Tomas T Furukawa Hiro H
Structure (London, England : 1993) 20160501 5
Signal transduction across cell membranes often requires assembly of heteromeric receptors with defined stoichiometry. In this issue of Structure, Morales-Perez et al. (2016) present elegant methods for the expression of heteromeric nicotinic acetylcholine receptors with a defined α4β2 stoichiometry involving controlled baculovirus-mediated transduction and subunit counting by measurement of two fluorescent signals. ...[more]
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