Ontology highlight
ABSTRACT:
SUBMITTER: Hu YF
PROVIDER: S-EPMC5266700 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Frontiers in microbiology 20170126
Bacterial surface proteins can be good vaccine candidates. In the present study, we used polyclonal antibodies purified with intact <i>Erysipelothrix rhusiopthiae</i> to screen phage-displayed random dodecapeptide and loop-constrained heptapeptide libraries, which led to the identification of mimotopes. Homology search of the mimotope sequences against <i>E. rhusiopthiae</i>-encoded ORF sequences revealed 14 new antigens that may localize on the surface of <i>E. rhusiopthiae</i>. When these puta ...[more]