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Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals.


ABSTRACT: A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identify genes and/or loci involved in the pathogenesis of the condition.

SUBMITTER: Takahashi M 

PROVIDER: S-EPMC5267165 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals.

Takahashi Masahiro M   Hosomichi Kazuyoshi K   Yamaguchi Tetsutaro T   Yano Keisuke K   Funatsu Takahiro T   Adel Mohamed M   Haga Shugo S   Maki Koutaro K   Tajima Atsushi A  

Human genome variation 20170126


A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identify genes and/or loci involved in the pathogenesis of the condition. ...[more]

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