Ontology highlight
ABSTRACT:
SUBMITTER: Wen J
PROVIDER: S-EPMC5269723 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Wen Jian J Wu Yongbin Y Wei Wei W Li Zhen Z Wang Ping P Zhu Shiwei S Dong Wenqi W
Scientific reports 20170127
Alcoholic liver disease (ALD) is an important worldwide public health issue with no satisfying treatment available since now. Here we explore the effects of recombinant human cytoglobin (rhCygb) on chronic alcohol-induced liver injury and the underlying mechanisms. In vivo studies showed that rhCygb was able to ameliorate alcohol-induced liver injury, significantly reversed increased serum index (ALT, AST, TG, TC and LDL-C) and decreased serum HDL-C. Histopathology observation of the liver of ra ...[more]