Systems-level metabolism of the altered Schaedler flora, a complete gut microbiota.
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ABSTRACT:
SUBMITTER: Biggs MB
PROVIDER: S-EPMC5270571 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
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Systems-level metabolism of the altered Schaedler flora, a complete gut microbiota.
Biggs Matthew B MB Medlock Gregory L GL Moutinho Thomas J TJ Lees Hannah J HJ Swann Jonathan R JR Kolling Glynis L GL Papin Jason A JA
The ISME journal 20161108 2
The altered Schaedler flora (ASF) is a model microbial community with both in vivo and in vitro relevance. Here we provide the first characterization of the ASF community in vitro, independent of a murine host. We compared the functional genetic content of the ASF to wild murine metagenomes and found that the ASF functionally represents wild microbiomes better than random consortia of similar taxonomic composition. We developed a chemically defined medium that supported growth of seven of the ei ...[more]
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