Ontology highlight
ABSTRACT:
SUBMITTER: Toepfer P
PROVIDER: S-EPMC5272812 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Toepfer Philipp P Heim Christine C Entringer Sonja S Binder Elisabeth E Wadhwa Pathik P Buss Claudia C
Neuroscience and biobehavioral reviews 20161224
Severe stress in early life, such as childhood abuse and neglect, constitutes a major risk factor in the etiology of psychiatric disorders and somatic diseases. Importantly, these long-term effects may impact the next generation. The intergenerational transmission of maternal early life stress (ELS) may occur via pre-and postnatal pathways, such as alterations in maternal-fetal-placental stress physiology, maternal depression during pregnancy and postpartum, as well as impaired mother-offspring ...[more]