Ontology highlight
ABSTRACT:
SUBMITTER: Ning LJ
PROVIDER: S-EPMC5282496 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Ning Li-Jun LJ He An-Yuan AY Lu Dong-Liang DL Li Jia-Min JM Qiao Fang F Li Dong-Liang DL Zhang Mei-Ling ML Chen Li-Qiao LQ Du Zhen-Yu ZY
Scientific reports 20170131
Peroxisome proliferation activated receptor α (PPARα) is an important transcriptional regulator of lipid metabolism and is activated by high-fat diet (HFD) and fibrates in mammals. However, whether nutritional background affects PPARα activation and the hypolipidemic effects of PPARα ligands have not been investigated in fish. In the present two-phase study of Nile tilapia (Oreochromis niloticus), fish were first fed a HFD (13% fat) or low-fat diet (LFD; 1% fat) diet for 10 weeks, and then fish ...[more]