Ontology highlight
ABSTRACT:
SUBMITTER: Ojha A
PROVIDER: S-EPMC5282509 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Ojha Amrita A Nandi Dipika D Batra Harish H Singhal Rashi R Annarapu Gowtham K GK Bhattacharyya Sankar S Seth Tulika T Dar Lalit L Medigeshi Guruprasad R GR Vrati Sudhanshu S Vikram Naval K NK Guchhait Prasenjit P
Scientific reports 20170131
Thrombocytopenia is common in patients with dengue virus (DENV) infections. With a focus on understanding the possible mechanism of thrombocytopenia in DENV infections we described a direct correlation between activation and depletion of platelets in patients. Our data showed a sharp decrease in platelet counts at day 4 of fever in patients. The high DENV genome copies in platelets correlated directly with the elevated platelet activation along with increased binding of complement factor C3 and ...[more]