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A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention.


ABSTRACT: A novel Janus device with omniphobic and mucoadhesive sides that exhibit the unique capacity for antifouling and extended gastrointestinal retention is fabricated. This system enables repulsion of the food and fluid stream by the luminal-facing omniphobic side and allows attachment to the gastrointestinal mucosa by the mucoadhesive side.

SUBMITTER: Lee YA 

PROVIDER: S-EPMC5283723 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention.

Lee Young-Ah Lucy YA   Zhang Shiyi S   Lin Jiaqi J   Langer Robert R   Traverso Giovanni G  

Advanced healthcare materials 20160406 10


A novel Janus device with omniphobic and mucoadhesive sides that exhibit the unique capacity for antifouling and extended gastrointestinal retention is fabricated. This system enables repulsion of the food and fluid stream by the luminal-facing omniphobic side and allows attachment to the gastrointestinal mucosa by the mucoadhesive side. ...[more]

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