Neural Signaling Metabolites May Modulate Energy Use in Hibernation.
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ABSTRACT:
SUBMITTER: Drew KL
PROVIDER: S-EPMC5284051 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Publications
Neural Signaling Metabolites May Modulate Energy Use in Hibernation.
Drew Kelly L KL Frare Carla C Rice Sarah A SA
Neurochemical research 20161123 1
Despite an epidemic in obesity and metabolic syndrome limited means exist to effect adiposity or metabolic rate other than life style changes. Here we review evidence that neural signaling metabolites may modulate thermoregulatory pathways and offer novel means to fine tune energy use. We extend prior reviews on mechanisms that regulate thermogenesis and energy use in hibernation by focusing primarily on the neural signaling metabolites adenosine, AMP and glutamate. ...[more]
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