Ontology highlight
ABSTRACT:
SUBMITTER: Rady M
PROVIDER: S-EPMC5286401 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Rady Mona M Watzl Carsten C Claus Maren M Khorshid Ola O Mahran Laila L Abou-Aisha Khaled K
Scientific reports 20170201
MicroRNAs (miRNAs) play an important role in regulating gene expression and immune responses. Of interest, miR-181a and miR-146a are key players in regulating immune responses and are among the most abundant miRNAs expressed in NK cells. Bioinformatically, we predicted miR-181a to regulate the expression of the natural cytotoxicity receptor NCR2 by seeded interaction with the 3'-untranslated region (3'-UTR). Whereas, miR-146a expression was not significantly different (P = 0.7361), miR-181a expr ...[more]