Ontology highlight
ABSTRACT:
SUBMITTER: Schlitter AM
PROVIDER: S-EPMC5286512 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Schlitter Anna Melissa AM Segler Angela A Steiger Katja K Michalski Christoph W CW Jäger Carsten C Konukiewitz Björn B Pfarr Nicole N Endris Volker V Bettstetter Markus M Kong Bo B Regel Ivonne I Kleeff Jörg J Klöppel Günter G Esposito Irene I
Scientific reports 20170201
Pancreatic ductal adenocarcinoma (PDAC) has generally a poor prognosis, but recent data suggest that there are molecular subtypes differing in clinical outcome. This study examines the association between histopathologic heterogeneity, genetic profile, and survival. Tumor histology from 177 resected PDAC patients with follow-up data was subclassified according to predominant growth pattern, and four key genes were analyzed. PDACs were classified as conventional (51%), combined with a predominant ...[more]