Ontology highlight
ABSTRACT:
SUBMITTER: Willems N
PROVIDER: S-EPMC5287222 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Willems Nathalie N Lelimousin Mickaël M Koldsø Heidi H Sansom Mark S P MS
Biochimica et biophysica acta. Biomembranes 20161218 3
Lipases are enzymes of biotechnological importance that function at the interface formed between hydrophobic and aqueous environments. Hydrophobic interfaces can induce structural transitions in lipases that result in an increase in enzyme activity, although the detailed mechanism of this process is currently not well understood for many lipases. Here, we present a multi-scale molecular dynamics simulation study of how different interfaces affect the conformational dynamics of the psychrophilic ...[more]