Ontology highlight
ABSTRACT:
SUBMITTER: Dushay JR
PROVIDER: S-EPMC5287335 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Journal of the renin-angiotensin-aldosterone system : JRAAS 20130513 2
<h4>Objective</h4>The objective of this paper is to study the effect of aliskiren on metabolic parameters and micro- and macrovascular reactivity in individuals diagnosed with or at high risk for developing type 2 diabetes mellitus (T2DM).<h4>Research design and methods</h4>We studied 47 T2DM and 41 at-risk individuals in a randomized, double-blinded, placebo-controlled trial. All subjects were treated with 150 mg aliskiren or placebo daily for 12 weeks. Twenty-six (55%) of T2DM and four (8%) at ...[more]