Ontology highlight
ABSTRACT:
SUBMITTER: Schorb M
PROVIDER: S-EPMC5287355 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Schorb Martin M Gaechter Leander L Avinoam Ori O Sieckmann Frank F Clarke Mairi M Bebeacua Cecilia C Bykov Yury S YS Sonnen Andreas F-P AF Lihl Reinhard R Briggs John A G JAG
Journal of structural biology 20160628 2
Correlative light and electron microscopy allows features of interest defined by fluorescence signals to be located in an electron micrograph of the same sample. Rare dynamic events or specific objects can be identified, targeted and imaged by electron microscopy or tomography. To combine it with structural studies using cryo-electron microscopy or tomography, fluorescence microscopy must be performed while maintaining the specimen vitrified at liquid-nitrogen temperatures and in a dry environme ...[more]